How Common are Glycogen Storage Diseases in Companion Animals?

How Common is Glycogen Storage Diseases (GSDs) in Companion Animals? GSDs are congenital diseases caused by disorders in the metabolism or synthesis of glycogen, a substance within cells that serves as a storage form of glucose. Most glycogen storage disease-affected dogs exhibit symptoms after birth or early childhood. Breeds commonly diagnosed with these disorders include the Doberman pinscher, greyhound, and Shar-Pei.

Introduction

Glycogen storage disease describes a group of rare genetic disorders that affect the way the body handles glycogen. Glycogen is a molecule used to store energy in the body, similar to starch or glucose. The symptoms of these conditions can vary between patients and may include exercise intolerance, elevated blood lactate, cardiac arrhythmia (irregular heartbeat), and a lack of muscle coordination. In companion animals, these diseases occur even less common than in humans.

Glycogen Storage Diseases in Companion Animals

Glycogen storage diseases are a group of disorders that affects the body’s ability to store and use glucose.

Glucose is a type of sugar that is essential for energy production, so if you have a glycogen storage disease, your body cannot process it properly. The most common type of glycogen storage disease is called Pompe.

In dogs, Pompe can cause sudden death due to heart failure and may also cause weakness or paralysis in the legs. A dog who has this disease will typically be diagnosed at an early age, but it’s important to know how common this disease is in companion animals so you can take steps to prevent it from happening.

How Common Is Pompe In Dogs?

Pompe is one of the most common types of glycogen storage diseases in dogs, which means that it’s relatively easy to diagnose and treat. Although there haven’t been many studies conducted specifically on Pompe in dogs, it’s estimated that anywhere between 1-5% of puppies born may have this condition.